A.D.A.P.T. Program Aims to Establish the First Portable, Networked Architecture for Domestic Manufacturing
[Center Valley, PA, June 2, 2026] — Skellig Manufacturing announces it has been selected to lead the Accelerated Distribution Architecture for Portable recipe Transfer (A.D.A.P.T.) program, a jointly funded initiative by the Defense Advanced Research Projects Agency (DARPA) Biological Technologies Office (BTO) and the Center for Industrial Base Management and Supply Chain (IBMSC) within the U.S. Department of Health and Human Services’ Administration for Strategic Preparedness and Response. The program represents a foundational investment in solving one of the most persistent vulnerabilities in U.S. national security: the inability to rapidly mobilize domestic manufacturing capacity in response to supply chain disruptions, pandemics, or defense emergencies.
Skellig will develop and validate the A.D.A.P.T platform, which uses structured data models to encode manufacturing processes as portable digital recipes, capable of executing across geographically distributed facilities without the years-long technology transfer typically required. If successful, the A.D.A.P.T. platform lays the technical and regulatory groundwork for an Internet of Medicines: a networked grid of sovereign, domestically operated manufacturing nodes that can be activated on demand, transforming the United States’ response to a pharmaceutical crisis from improvised scrambling into coordinated, decisive action.
In partnership with ASPR’s IBMSC, A.D.A.P.T. researchers also aim to advance the onshoring of active pharmaceutical ingredient (API) production for critical medicines that the United States has historically sourced from overseas suppliers. By establishing domestic API manufacturing capacity and progressing the regulatory pathway through a Drug Master File submission to the Food and Drug Administration (FDA), Skellig’s work will support the broader national imperative to build a resilient, responsive domestic public health supply chain, ensuring that essential medicines, medical countermeasures, and their critical inputs can be reliably produced on American soil and mobilized when they matter most.
“The United States has a highly skilled manufacturing workforce and
infrastructure, we just haven’t given it the connective tissue it needs to
work together. A.D.A.P.T. is about using digital tools to unlock the capacity
that already exists, making it smarter, faster, and far more responsive to
the moments that matter most. When the next shortage hits or the next
crisis arrives, we want the answer to already be on the shelf, not three
years away.”
— Jennifer Jones, Chief Executive Officer, Skellig Manufacturing
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